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Newer compounds like Tirzepatide or Retatrutide, which act on multiple receptors like GLP-1 and GIP, represent the next frontier in this area, offering even more complex and powerful metabolic modulation to study alongside IGF-1 LR3's anabolic signaling

(2007) Insulin-Like Growth Factor-I, Regulating Aromatase Expression through Steroidogenic Factor 1, Supports Estrogen-Dependent Tumor Leydig Cell Proliferation Elisabetta Scarano, et al

The level of growth hormone in the blood is measured to assess how the pituitary is working, as outlined by the MedlinePlus overview of the growth hormone blood test