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Kazantseva MG, Highton J, Stamp LK, Hessian PA

The primary function of cGAS-STING signaling is to trigger the innate immune response by inducing IFN-I production and subsequent interferon-stimulated gene (ISG) expression (16, 17)

however, this represents early-phase evidence only, and the mechanistic effects observed in trials including increased energy expenditure and lipolysis via glucagon receptor agonism have not yet been fully characterised in long-term human studies

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Since 2020, there has been a continual rise in unusual and alarming health issues emerging world-wide, affecting all age groups