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Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver

Other inducers of erythrocyte death and concomitant ATP depletion include metals such as chromium [184], metalloids such as arsenic [185], riboflavin and UV light during RBC storage [186], and the phospholipid signaling molecule lysophosphatidic acid [187]

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Recent studies have found that interleukin-1 receptor 1 (IL1R1), gut microbiota, and BA changes synergistically contribute to the development of MASLD [40], suggesting pathogenic cross-talks between BA metabolism, gut dysbiosis, and metaflammation , i.e., sterile metabolic inflammation, in MASH

HDV status was modeled as a time-varying covariate to account for the effects of the wait time between the date of CHBV diagnosis and the first record for HDV diagnosis