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Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration

Once in the tissues, ALA can be found inside and outside the cells including inside the mitochondria where it functions naturally as a coenzyme for the oxidation of pyruvate, alpha ketoglutarate, and branched-chain amino acids.*

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Standard testing options include: Optimal testing frequency depends on individual risk factors, with high-risk individuals requiring more frequent monitoring to prevent deficiency complications

[149] The few studies that have used equivalent (weight-adjusted) human therapeutic doses and oral administration show that these changes, if they occur, are relatively minor