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The TNF- treatment of human keratinocytes increased the expression of 26 genes involved in inflammatory pathways, including chemokines like CXCL8 and CXCL10

Here are some of the drugs shown to affect melatonin: Antidepressants including Fluoxetine (Prozac), Paroxetine (Paxil), Sertraline (Zoloft), Citalopram (Celexa), Escitalopram (Lexapro), Venlafaxine (Effexor) Benzodiazepines including Diazepam (Valium), clorazepate (Tranxene), lorazepam (Ativan), Clonazepam (Klonopin), Alprazolam (Xanax) Antipsychotics including Aripiprazole (Abilify), Quetiapine (Seroquel), Risperidone (Risperdal), Olanzapine (Zyrexa), Haloperidol (Haldol), Paliperidone (Invega), Ziprasidone (Geodon) If you take one of these drugs, you should consider supplementing with melatonin every night

Minich T, Riemer J, Schulz JB, Wielinga P, Wijnholds J, Dringen R (2006) The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes

First, the effect is reproduced across multiple large Phase 3 trials in different populations, not a single program

& Bucciantini, M