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Ferroptosis suppression is achieved through dual mechanisms, GPX4 employs glutathione to detoxify lipid hydroperoxides, while deferoxamine chelates intracellular iron, limiting Fe 2+ for Fenton chemistry and consequently attenuating reactive oxygen species generation and membrane lipid oxidation (153)

doi: 10.2967/jnumed.119.227140 72 KangU

This controlled elimination of compromised cells aids their clearance and fosters subsequent mucosal repair and regeneration (167)

In turn, Magnussen collaborated with notorious Nazi physician Josef Mengele

Childs BG, Durik M, Baker DJ, van Deursen JM (2015) Cellular senescence in aging and age-related disease: from mechanisms to therapy