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Anthracyclines, including DOX, have demonstrated an impact on protein degradation pathways in adult cardiomyocytes

Following histologic diagnosis, the treatment of the HPV-induced lesions depends on the degree of severity: while ASCUS/CIN1 need no treatments at the time of diagnosis as most of them regress spontaneously, high-grade lesions (HSIL/CIN2 or CIN3) may undergo conservative surgical procedures, including ablative methods that destroy the affected cervical tissue [12]

Moreover, mitochondria depletion prevented ferroptosis induced by cysteine-deprivation or Erastin 36