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Zingale E, Rizzo S, Bonaccorso A, Consoli V, Vanella L, Musumeci T, et al

Release of inhibition by metformin on the accumulated expression of respiratory complex transcripts in B cells at this point could have thus supported more efficient OXPHOS and hence antibody expression

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Moreover, early studies have shown that oxidative stress alone can induce tunneling nanotube formation, depending on stress sensing factors such as p53 [382]

Insulin resistance, associated with mitochondrial dysfunction and increased production of ROS, alters the cardiovascular, renal, and neural functions of insulin and is a risk factor for microvascular disease