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We observed significant differences between Wt+R+V (mean latency to fall 54.84 6.13 SEM, mean grip strength 6.37 0.23 SEM) and healthy Wt+V controls (mean latency to fall 84.57 5.78 SEM, p = 0.01 mean grip strength 7.28 0.22 SEM, p = 0.03) (Fig

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Pro dehydrogenase metabolism maintains mtROS homeostasis via sirtuin 1/superoxide dismutase 2 pathways

The above studies also suggest that ROS generation, upregulation of p53, and reduction of mitochondrial membrane potential play important roles in selenium-assisted anti-tumor processes