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The regulation of blood glucose by melatonin occurs through the direct binding to melatonin receptors (the receptors of melatonin are present in the pancreatic -cells which modulates the secretion of insulin) [86]

The first GPX4 inhibitor RSL3 has been proven effective in suppressing gliomas by stimulating GPX4 inactivity in a dose-dependent manner[119]

Fu Y-S, Chen T-H, Weng L, Huang L, Lai D, Weng C-F (2021) Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential