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For tissue samples, approximately 0.1 g of mouse skin tissue was homogenized on ice in 1 mL of cold PBS, and the supernatant was collected after centrifugation (8,000 g, 10 min, 4 C)

NAC hepatoprotective effects may be attributed to its antioxidant capacity in drug-induced hepatotoxicity (Maheswari et al., 2014

Mice null for Fbxo40 have increased levels of IRS1 and demonstrate enhanced body and muscle size during the growth phase associated with elevated IGF1 levels. Moreover, IGF-1 LR3 also helps with muscle repair via improving the proliferative capacity of muscle satellite cells (MSCs)

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Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., Nakajima, A