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Simultaneous homotopic transplantation of fetal dopaminergic progenitors into the ventral midbrain of 6-OHDA-lesioned mice together with ChABC injected into the nigrostriatal bundle did not affect graft survival, but significantly enhanced axonal growth along the nigrostriatal pathway and increased reinnervation of the striatum compared to untreated grafted controls (Kauhausen et al., 2015)

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In summary, while cuproptosis is centered on metabolic toxicity, pyroptosis focuses on inflammatory signaling

Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase Redox Biol