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In modern biochemistry, these are referred to as reactive O2 species

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Ogata and Hirasawa 2021)

Other amino acids may enter the cycle as succinyl-CoA, fumarate or pyruvate

USA 85 64656467 Roper JM, Mazzatti DJ, Watkins RH, Maniscalco WM, Keng PC and OReilly MA 2004 In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells

Studies demonstrate that it may cause liver damage when used in large amounts for longer than 3 months ( Summary Senna is a common ingredient in laxative products and may be an effective treatment for constipation