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Milk thistle extract contains an antioxidant and an anti-inflammatory called silymarin that has been shown to help ease inflammation and promote cell repair within the liver

It also incorporates interactions with human hosts, highlighting the roles of innate and adaptive immunity including immune invasion and evasion tactics

Rather, evidence for these alterations has been collected piecemeal, limiting the potential to inform our understanding of the interactions amongst relevant biochemical pathways

With better refinement of existing strategies and development of new therapies to prevent and treat CAR T-cell related toxicities, more patients, through new disease indications or various clinical settings, would safely benefit from this novel treatment modality