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Among vectors preferred for use in bacteria include pQE70, pQE60 and pQE-9, available from QIAGEN, Inc

This causes DNA damage and formation of ONOO due to excess NO (nitrosative stress) and other free radicals

556 Consequently, researchers believe that HIF-1 may serve as a mechanism for cells to rapidly respond to acute hypoxia, whereas HIF-2 may be more relevant in chronic hypoxic responses