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NF-B, as a transcriptional regulator of DNA, plays a crucial role in the expression of more than 200 genes involved in immune and inflammatory responses 40,41

TNF- acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle

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You may be familiar with the acronym ATP, as this is the primary chemical form used for the energy needed for cellular processes, including the contraction of muscle proteins to perform exercise and the production of new proteins