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However, only pimitespib, an oral inhibitor developed by Taiho Pharmaceutical, was approved in Japan in 2022 for gastrointestinal stromal tumors, and it is currently the focus of a phase I study for the treatment of solid tumors in the EU and USA [7, 8]

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Med Clin North Am 96(2):269281 de Bruin TW, van Barlingen H, van Linde-Sibenius Trip M, van Vuurst de Vries AR, Akveld MJ, Erkelens DW

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