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Bning Journal: Molecular therapy : the journal of the American Society of Gene Therapy Journal ranking: Q1 Key takeaways: Tropism-modified AAV vectors with novel receptors significantly improve cutaneous gene therapy by increasing cell entry efficiency and targeting v8 integrin, overcoming safety concerns.

A dose that supports one organ system may be excessive for another

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One mouse and cage were excluded from vehicle group due to the development of constipation