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Vitamin B-12 is also needed for neurotransmitter signaling that helps your muscles contract and gives you energy to go about your day without feeling tired and run down

4 Discussion This systematic review and meta-analysis provide a comparative evaluation of oral, sublingual, and intramuscular (IM) vitamin B12 supplementation in the management of B12 deficiency

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Signs of vitamin B6 deficiency include dermatitis (skin inflammation), glossitis (a sore tongue), depression, confusion and convulsions

Although gastric banding carries a lower risk of B12 deficiency than malabsorptive procedures such as Roux-en-Y bypass, reduced tolerance of B12-rich foods and the use of acid-suppressing medicines can still compromise nutritional status over time