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The observed protective effect coincided with alterations in the expression of genes associated with oxidative balance (Noxa1, Gpx1, Ccs, and Sod1) and inflammation (Mpo, Ncf, Il1b, and Il4)

Screening of 289 patients with coronary artery disease and 255 control subjects revealed 77 individuals with the G-50T SNP (17.3% of CAD patients, 10.6% of control subjects