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In addition, the receptor for bile acids, farnesoid X receptor (FXR) is found to be downregulated in MASLD (132)

Kim J, John J, Langford D, Walker E, Ward S, Rawls SM

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3,2,10 As a key component of GPx, selenium neutralizes reactive oxygen species (ROS), which limits lipid peroxidation by free radicals and lowers oxidative stress-induced cellular damage and inflammation

Thus, amygdalin has been shown in vitro experiments to induce apoptosis due to upregulated expression of caspase-3 and Bax protein and downregulated expression of Bcl-2, an anti-apoptotic protein (217) ( Table 2 )