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While Spirulina presents a promising sustainable resource, it is crucial to recognize that, like other bio-based systems, its production often involves energy-intensive processes

Compared with CuZnHis(L), CuZnHis(D) assemblies have stronger inhibitory effect on lipid peroxidation reactions, manifested as lower intracellular MDA level and stronger ability to resist oxidative stress injury (Fig

Potential interventions include pharmacological inhibition of RIPK1 (e.g., necrostatins) or RIPK3, as well as modulation of MLKL activity to block execution of necroptosis

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