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Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors

The following figure illustrates the dual potential of ferroptosis in GC treatment ( Figure 5 )

doi: 10.3389/fnut.2026.1676497 Received 30 July 2025 Revised 18 December 2025 Accepted 05 January 2026 Published 13 February 2026 Volume 13 - 2026 Edited by Senthil Kumaran Satyanarayanan, Hong Kong Institute of Innovation and Technology, Hong Kong SAR, China Reviewed by Luciene Bruno Vieira, Federal University of Minas Gerais, Brazil Iffet Ipek Bosgelmez, Erciyes University, Trkiye Updates Copyright 2026 Miteva, Laurenti, Mattioli, Di Risola, Mariano and Mosca

In young children, iron deficiency also can lead to cognitive impairment, but it is not known if developing iron deficiency in adolescence would have the same effect

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