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460 In line with this, a similar finding was found by different investigators 461 and further evidence associates the regulation of immunometabolism of macrophages with other ageing-related diseases, such as type 2 diabetes 462 and macular degeneration

Eisa EA, Honfi P, Tilly-Mndy A, Mirmazloum I

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Thus, cGAS-STING signaling appears to be essential for the pathogenic activities of FLSs, and this signaling represents a promising target to prevent the aberrant activation of FLSs for RA treatments