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References Aderao GN, Jadhav SE, Pattanaik AK, Gupta SK, Ramakrishnan S, Lokesha E, Chaudhary P, Vaswani S, Singh A, Panigrahi M, Dutta N (2023) Dietary selenium levels modulates antioxidant, cytokine and immune response and selenoproteins mRNA expression in rats under heat stress condition

Wrinkle reduction Yes Regeneration and healing Yes Antioxidant effects Yes Improved skin elasticity Yes Safety of use Yes Scientific data and sources Research summary Level of evidence Preliminary Number of included studies: 20 8 studies 5 studies 4 studies 1 study 1 study 1 study Final comment: Although systematic literature analyses and results from in vitro and animal model studies indicate the effectiveness of GHK-Cu in skin regeneration and wrinkle reduction, there are no direct randomized controlled trials in humans