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Menter T, Haslbauer JD, Nienhold R, Savic S, Hopfer H, Deigendesch N, et al

333 It is reported that LRRK2 G2019S dopaminergic neurons exhibit a decreased NAD + pool and a reduced sirtuin deacetylase activity, correlating with elevated acetylation of sirtuin substrates p53, -tubulin and SOD2