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This highly hydrophobic bile acid can promote hepatic cholesterol hypersecretion and cholesterol crystallization

The main circulating androgen is testosterone, which is produced in the Leydig cells of the testis and can also act as a pro-hormone after being metabolized to dihydrotestosterone (DHT) or estradiol (E 2 )

For instance, metabolomic profiling of frozen tilapia muscle revealed decreases in flavour-enhancing amino acids and nucleotides, alongside increases in off-flavour compounds from protein and lipid degradation [129]