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In addition to the colocalization of Fas with raft markers, the researchers also detected the presence of FasL, FADD, and activated caspase-8, further supporting the formation of a functional DISC in aged RBCs

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Xiao B, Zhang M, Viennois E, Zhang Y, Wei N, Baker MT et al (2015) Inhibition of MDR1 gene expression and enhancing cellular uptake for effective colon cancer treatment using dual-surface-functionalized nanoparticles