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I think the positive that comes from this is now we have sort of a call to action and an obligation, Kerr-German said

Importantly, commonly used in vitro BBB models, such as transwell systems and endothelial cell lines including RBE4, bEnd.3, and hCMEC/D3 monolayers, have important limitations, as they may overpredict permeability and do not fully recapitulate key in vivo BBB features, including physiological shear stress and multicellular neurovascular architecture (Katt and Shusta, 2020)

In contrast to apoptosis, necrosis, and autophagy, ferroptosis is characterized by the build-up of lipid reactive oxygen species (ROS) triggering membrane damage

Avoid direct exposure to light and frequent temperature changes to prevent premature peptide degradation

Outcomes are individual