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Current Obesity Reports, 8(2), 156164.

Bottom line: B12 is essential for our health at all ages

N G -nitro-L-arginine methylester (L-NAME) (5 mg/kg i.v.), a competitive inhibitor of endothelium nitric oxide (NO)-generation and the NO-precursor L-arginine (200 mg/kg i.v.) (D-arginine was ineffective)

"Insulin resistance and endothelial function are improved after folate and vitamin B12 therapy in patients with metabolic syndrome: relationship between homocysteine levels and hyperinsulinemia"

Some patients experience appetite suppression after their first injection while others have to work up in dosage to achieve this result