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At first, he said, the experience seemed positive

doi: 10.1182/blood-2011-03-340281 158 DaiRPhillipsRAKarpuzogluEKhanDAhmedSA

Overall occurrence of this syndrome is low at about 0.05% of hospitalized patients with low sodium, but risk increases sharply when sodium starts below 110 milliequivalents per liter, jumping to 2.6% occurrence

Its clinical adoption is significantly hampered by practical limitations, including an intravenous-only administration route unsuitable for long-term or outpatient care and a narrow therapeutic window

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