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FIGURE 3 6.1.2 COX-2-PGE 2 -EP4 axis in RCC In most cell types, activated EP4 receptors are regulated by lipids and intracellular messengers such as cAMP (Fong et al., 2021) (Figure 3)

Additionally, in vivo barcoding technologies, including those using adeno-associated viruses (AAVs), enable the tracking of tumor evolution in more physiologically relevant contexts [160]