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Additionally, localized and systemic immunosuppression is also induced

For laboratory preparation, researchers typically reconstitute with bacteriostatic water, added slowly down the inside wall of the vial and swirled gently rather than shaken

In addition, capsaicin upregulates PTEN-induced kinase 1 (PINK1) and Parkin expression, thereby enhancing mitophagy and reducing hepatic lipid accumulation (45)