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Acyl-CoA synthetase long chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 are key enzymes involved in the process of lipid peroxidation (52)

2 The term venous insufficiency is interchangeable with the terms venous incompetence, venous hypertension and venous congestion, and indicates elevated intravenous pressure that can lead to well-recognised skin and vein complications (Box 1 and Figure 2)

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10.1186/s12967-023-04719-x 77 HuY.ChenX.HuM.ZhangD.YuanS.LiP.et al (2022)