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Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs

It consists largely of three amino acids: glutamine, glycine, and cysteine

Dihydroartemisinin attenuates lipopolysaccharide-induced acute lung injury in mice by suppressing NF-B signaling in an Nrf2-dependent manner

This approach not only produces synergistic effects across these levels but also enhances drug delivery efficiency and mucosal retention through the use of natural polymeric materials, thereby comprehensively improving the efficacy of 5-ASA ( FIGURE 2 2.2 Combination of TCM formulations and 5-ASA: holistic multi-target regulation The combination of TCM formulations with 5-ASA demonstrates multidimensional synergistic advantages in clinical efficacy, mechanisms of action, and safety, significantly expanding the scope of disease management beyond conventional 5-ASA monotherapy

examined the stability of different formulations of LNPs loaded with mRNA (mRNA-LNPs) before and after nebulization using a VMN [141]