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Interestingly, venous ammonia levels significantly improved in treatment groups (but not in placebo) independently of neurocognitive changes

Second, the regulation of immune cell repair pathways exhibits high heterogeneity

These saponin components act through multiple targets and pathways, including anti-oxidative stress, anti-inflammatory, and anti-apoptotic mechanisms

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Importantly, it also reversed MPTP-induced dysbiosis, reducing harmful taxa ( Citrobacter , Desulfovibrio , Ruminococcus ) and restoring beneficial bacteria such as Dubosiella