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The current study clarified a novel mechanism by which the ROS/HO1/GPX4 axis mediates the protection against cisplatin-induced renal tubular epithelial cell ferroptosis for both BNIP3-mediated and PINK1-PARK2-mediated mitophagy [58]

It is found in a variety of foods such as fish, shellfish, meats, and dairy products

Obesity inhibits the hypothalamic-pituitary-gonadal axis, disrupting ovarian function, ovulation index and endometrial receptivity, and affects the molecular mechanisms that regulate the biological activity of the reproductive system (3, 181, 182)

The formation of colonies was further impaired in ADH5 GCLM cells compared to ADH5 -single knockout counterparts, thus revealing an independent contribution of GSH biosynthesis and ADH5 to this phenotype (Fig