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Hcy self-oxidation generates ROS, disrupts redox homeostasis, and induces neuronal apoptosis via upregulation of Bax protein expression and activation of the caspase-3 pathway ( MMA further contributes to oxidative stress by impairing the mitochondrial respiratory chain complexes and energy metabolism

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126 Initially, a GHGHBP fusion protein agonist was generated for the treatment of GH deficiency

Biomarkers that can predict the occurrence of chemoresistant or relapsed tumors are rare (45), especially in GC

Regner, Erika L