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Studies have shown that trypsin induces the release of calcium ions from vascular endothelial cells, causing coronary artery-dependent vasodilation and reducing the contractile sensitivity of smooth muscle [79]

10.1038/s41380-023-02161-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 84.Cheng X, Zhang Y, Li Y, Wu Q, Wu J, Park SK, et al

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doi: 10.1113/ep092191 Low-volume combined aerobic and resistance high-intensity interval training in type 2 diabetes: a randomised controlled trial

The pre-Btzinger complex is necessary for the expression of inspiratory and post-inspiratory motor discharge of the vagus