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Antioxidants in the foods we eat can neutralize the unstable molecules, reducing the risk of damage

For example, a three-month course of lactulose therapy significantly improved sleep quality, reduced daytime sleepiness, and increased sleep duration and REM sleep in patients with minimal HE ( Continuous positive airway pressure is the treatment of choice for OSA, improving sleepiness and potentially benefiting liver health

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Major causes of deficiency include decreased ileal absorption (Crohn's disease and ileal resection), decreased intrinsic factor (atrophic gastritis and post-gastrectomy), and inadequate intake (strict vegetarians, vegans, elderly, and alcoholics)

Sarchielli P, Zaffaroni M, Floridi A et al (2007) Production of brain-derived neurotrophic factor by mononuclear cells of patients with multiple sclerosis treated with glatiramer acetate, interferon- 1a, and high doses of immunoglobulins