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In a study by Shyh-Mirnin Ph.D

Regulation of T-cell function in lung tissue by pulmonary alveolar macrophages

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Exercise above the threshold levels of one hundred and fifty fitness points per week or working at 80% of predicted maximum heart rate for at least 5 hours per week may greatly increase the bodys production of excess free radicals, which can result in unwanted changes to the bodys tissues and cause cells to becomes more susceptible to aging