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Chemical research in toxicology, 2007, 20(9): 1309- 1314

Elderly, Cachectic, or Debilitated Patients Life-threatening respiratory depression is more likely to occur in elderly, cachectic, or debilitated patients because they may have altered pharmacokinetics, including clearance, compared to younger, healthier patients [see WARNINGS

Song E, Su C, Fu J, Xia X, Yang S, Xiao C et al

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