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Description

It interacts weakly with receptors such as ER/ER, but its principal actions arise from regulating intracellular signaling networks including NF-B, Nrf2, PI3K/AKT, PTEN, and TGF-/Smad

Proceedings of the National Academy of Sciences of the United States of America 113 , E56185627 (2016)

Wu et al., 2023), decreasing oxidizable PUFAs substrates in membrane phospholipids through dietary intervention or locally altering lipid composition (Li Y