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Vitamin B12 plays a foundational role in red blood cell production, neurological function, DNA synthesis, and energy metabolism

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However, the current available antibody assay has low sensitivity and studies have found that antibodies are only detectable in 4060% of pernicious anaemia cases, so a negative test cannot categorically exclude pernicious anaemia[18,19]

Tip: Semaglutide has a 7-day half-life (the longest among GLP-1s), meaning it takes 4-5 weeks to reach steady state at each dose tier