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AFPs are particularly promising because they can recognize multiple microbial targets, thus reducing the possibility of resistance development (Rautenbach et al., 2016), a topic that is discussed in more detail in the following section

Prostate cancer foundation white paper on combination therapy for metastatic hormone-sensitive prostate cancer

Aspiration It is common practice to draw back on a syringe after the needle has been inserted to check whether it is in a blood vessel

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For instance, Mn 2+ physiologically supports the catalytic activity of glutamine synthetase (GS) as an essential divalent metal cofactor, while excessive Mn exposure can toxicologically impair GS expression and/or activity and disrupt the broader glutamateglutamine (GluGln) cycling network, thereby increasing the glutamate burden and the risk of excitotoxicity 144,179