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Both terpene synthase genes (e.g., TES, TPD5/10/13 ) and carotenoid cleavage oxygenase gene (e.g., CCD4 ) that implicated in the biosynthesis of volatile terpenoids were specifically induced by CT

Mutating ENL E74 to alanine fully blocked ENL degradation by ( S )-dHTC1 while only modestly impacting SR-1114 activity (Fig

S2 MCDB131 (Corning, USA), 1% Glutamax (Thermo Fisher Scientific, Netherlands) + 1% Pen/Strep (Thermo Fisher Scientific, Netherlands), 2.44 mM glucose (Merck Millipore, USA), 13 mM sodium bicarbonate (Merck Millipore, USA), 2% BSA (Capricorn Scientific, USA), 2 l/100 mL ITS-X (Thermo Fisher Scientific, Netherlands)

Prabhakar NR, Overholt JL: Cellular mechanisms of oxygen sensing at the carotid body: Heme proteins and ion channels