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In addition, M1-mAChR may play a key role in the process of inhibiting ferroptosis

In an in vitro study of PQ-treated lung epithelial cells (MLE-12 cells), Quercetin was found to modulate the fibrotic process mediated by the TGF-1/Smad and Akt/mTOR signaling pathways, altering the expression of markers of the epithelial-mesenchymal transition (EMT) and inhibiting the onset of fibrosis, resulting in improved cell survival

& Tononi, G

[45] demonstrated that culturing TIG-1, WI-38, MRC-5, HeLa, and HepG2 cells with Pt nanozymes at concentrations up to 50 g/mL did not induce cytotoxicity, oxidative stress, or cell death