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CrossRef The Immunomodulatory and Regenerative Effect of Biodentine on Human THP1 Cells and Dental Pulp Stem Cells: In Vitro Study Duaa Abuarqoub, Nazneen Aslam, Rand Zaza, Hanan Jafar, Suzan Zalloum, Renata Atoom, Walhan Alshaer, Mairvat Al-Mrahleh, Abdalla Awidi, Bruna Sinjari BioMed Research International.2022;[Epub] CrossRef Biodentine: Material of choice for apexification Himanshu Aeran, Mahema Sharma, Avantika Tuli International Journal of Oral Health Dentistry.2021

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Figure 1 Cytochrome P450-Mediated Metabolic Activation APAP metabolic activation is mainly catalyzed by the cytochrome P450 enzyme and the reactive metabolite associated with hepatotoxicity is commonly considered to be NAPQI (Streeter et al., 1984)

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