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Diabetic neuropathy relief: strong evidence Alpha-lipoic acid (ALA) is one of the most well-researched supplements for diabetic peripheral neuropathy, a common complication of diabetes that can lead to nerve pain, tingling, numbness, and weakness in the limbs.19 Several clinical trials, particularly those involving intravenous ALA, have shown that doses of 600mg per day can reduce these symptoms over a matter of weeks.20 21 ALAs proposed benefit lies in its antioxidant activity

Notably, the isoform 3 of the carrier SLC44A4 has recently been described as a TPP carrier in the colon

[19] Because of its antioxidant role, GSS mostly produce GSH inside the cytoplasm of liver cells and imported to mitochondria where detoxification occurs

V6711, V6712, V6713, V6714, V6071, V6072, V6073, V6074, V3771, V3772, V3773, V3774

10.1242/dev.137075 253 YuanJ.ZhaoX.HuY.SunH.GongG.HuangX.et al (2018)