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Diagnosis: You must need the medication for weight loss and cannot have type 2 diabetes, moderate-to-severe sleep apnea, or fatty liver disease

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Thresholds for defining excessive B12 supplementation were based on the fact that an oral cyanocobalamine supplementation with 1000 g/week (or injectable supplements of 1000 g/month) is sufficient for most cases of B12 deficiency, except for pernicious anemia and some rare causes with limited absorption or trafficking of cobalamin [25]

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